Cesium hydroxide → 3,5-Dimethylphenol

HRID 1424756Notes

Reaction equation

HRID 1424756 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4](I)[CH:5]=[C:6]([CH3:8])[CH:7]=1.[OH-:10].[Cs+]>ClCCl.CCCCCCC>[CH3:1][C:2]1[CH:3]=[C:4]([OH:10])[CH:5]=[C:6]([CH3:8])[CH:7]=1

Participants

4

Reactant 2

HCID 62750Cesium hydroxideHCID 1409241-Iodo-3,5-dimethylbenzene

Product 1

HCID 79483,5-DimethylphenolYield 96%

Reagents, catalysts & solvents 1

HCID 21907733Dichloromethane heptaneSolvent

Procedure

Following general operating mode A, 3,5-dimethyliodobenzene (145 μL, 1.0 mmol) was reacted with cesium hydroxide to give the expected product in the form of a white solid with a yield of 96% (eluent: dichloromethane/heptane 20:80).

Sources & evidence

ORD record
ord-663a83ab21a846edb3862a9811e4fccf
Source dataset
uspto-grants-2015_01
Patent number
US08927779B2

Reaction notes

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