2-Bromonaphthalene → 2-Naphthol

HRID 1424760Notes

Reaction equation

HRID 1424760 reaction equation
Br[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=1.[OH-:12].[Cs+]>C(OCC)(=O)C.CCCCCCC>[CH:3]1[C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[CH:10]=[CH:11][C:2]=1[OH:12]

Participants

4

Reactant 2

HCID 113722-BromonaphthaleneHCID 62750Cesium hydroxide

Product 1

HCID 86632-NaphtholYield 88%

Reagents, catalysts & solvents 1

HCID 21899848Ethylacetate heptaneSolvent

Procedure

Following general operating mode B, 2-bromonaphthalene (207 mg, 1.0 mmol) was reacted with cesium hydroxide to give the expected product in the form of a white solid with a yield of 88% (eluent: ethyl acetat/heptane 20:80).

Sources & evidence

ORD record
ord-0413524aa3814d43b20eef7f89d778c9
Source dataset
uspto-grants-2015_01
Patent number
US08927779B2

Reaction notes

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