反应详情

The same operation as in Example (91d) was performed using ethyl trans(±)-2-[(2-{[(4-chloro-5-ethyl-1H-imidazol-2-yl)carbonyl]amino}-2,3-dihydro-1H-inden-5-yl)carbamoyl]cyclopropanecarboxylate obtained in Example (98b) (100 mg, 0.23 mmol), 2 N lithium hydroxide (3 mL, 6 mmol) and methanol (3 mL), to obtain 71 mg of the title compound as a colorless solid (76%).