Water → Tert-butyl 2-(6-(3,4-dimethoxyphenylcarbamoyl)benzo[d]thiazol-2-ylamino)ethyl(methyl)carbamate

HRID 142520Notes

Reaction equation

HRID 142520 reaction equation
[Br:1][c:2]1[s:3][c:4]2[c:5]([n:6]1)[cH:7][cH:8][c:9]([C:11](=[O:12])[NH:13][c:14]1[cH:15][c:16]([O:22][CH3:23])[c:17]([O:20][CH3:21])[cH:18][cH:19]1)[cH:10]2.[C:24]([CH3:25])([CH3:26])([CH3:27])[O:28][C:29]([N:30]([CH3:31])[CH2:32][CH2:33][NH2:34])=[O:35].[CH3:37][N:38]1[CH2:39][CH2:40][CH2:41][C:42]1=[O:43].[OH2:36]>>[c:2]1([NH:34][CH2:33][CH2:32][N:30]([C:29]([O:28][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:35])[CH3:31])[s:3][c:4]2[c:5]([n:6]1)[cH:7][cH:8][c:9]([C:11](=[O:12])[NH:13][c:14]1[cH:15][c:16]([O:22][CH3:23])[c:17]([O:20][CH3:21])[cH:18][cH:19]1)[cH:10]2

Participants

5

Reactant 4

HCID 962WaterHCID 13387N-methyl-2-pyrrolidoneHCID 2756424N-Boc-N-methylethylenediamineHCID 672362232-bromo-N-(3,4-dimethoxyphenyl)benzo[d]thiazole-6-carboxamide

Product 1

HCID 86654768Tert-butyl 2-(6-(3,4-dimethoxyphenylcarbamoyl)benzo[d]thiazol-2-ylamino)ethyl(methyl)carbamate

Sources & evidence

ORD record
ord-03d21e7abe47459ea8559319be0a8f8c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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