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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1425754Generated: October 31, 2026

4-Benzyloxy-1-[2-(4-hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one → 2-[2-(4-Hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-5-(5-methoxy-pyridin-2-ylmethoxy)-2H-pyridazin-3-one

https://huagongshe.com/reaction/1425754

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Benzyloxy-1-[2-(4-hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-oneHCID 86695537—
Reactant5-(5-Methoxy-pyridin-2-ylmethoxy)-2H-pyridazin-3-oneHCID 86695554—
Product2-[2-(4-Hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-5-(5-methoxy-pyridin-2-ylmethoxy)-2H-pyridazin-3-oneHCID 8669555570%

Reaction Steps

2-[2-(4-Hydroxymethyl-2-methyl-phenyl)-2-oxo-ethyl]-5-(5-methoxy-pyridin-2-ylmethoxy)-2H-pyridazin-3-one is prepared following preparation 1c employing 5-(5-methoxy-pyridin-2-ylmethoxy)-2H-pyridazin-3-one (preparation 9b) instead of 4-benzyloxy-1H-pyridin-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08933079B2
Source datasetuspto-grants-2015_01
ORD IDord-e4c78fe162fb44d6a5ccffe41da8200d
Source noteuspto-grants-2015_01