HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → 1-(6-Chloropyridin-3-yl)cyclopropane-1-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | 2-(6-Chloropyridin-3-yl)acetonitrile | HCID 1475128 | — |
| Product | 1-(6-Chloropyridin-3-yl)cyclopropane-1-carbonitrile | HCID 22159357 | 43% |
Reaction Steps
The title compound was prepared from (6-chloro-pyridin-3-yl)-acetonitrile and 1,2-dibromoethane following a procedure analogous to that described in Step 3 for Intermediate 4. Yield: 43% of theory; LC (method 3): tR=2.71 min; Mass spectrum (ESI+): m/z=179/181 (Cl) [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08933072B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-95b352639e8a465aad9489a99bdc1de6 |
| Source note | uspto-grants-2015_01 |