HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-hydroxypyridine → 1,1-Dimethylethyl 3-(4-bromo-2-oxo-1(2H)-pyridinyl)-1-azetidinecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-hydroxypyridine | HCID 817115 | — |
| Reactant | Tert-butyl 3-iodoazetidine-1-carboxylate | HCID 11000522 | — |
| Product | 1,1-Dimethylethyl 3-(4-bromo-2-oxo-1(2H)-pyridinyl)-1-azetidinecarboxylate | HCID 70651750 | — |
Reaction Steps
The title compound was prepared from 4-bromopyridin-2(1H)-one and 3-iodo-azetidine-1-carboxylic acid tert-butyl ester following a procedure analogous to that described for Intermediate 22.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08933072B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-7c15b827f7224a02a25cfd224d3547bd |
| Source note | uspto-grants-2015_01 |