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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1426002Generated: November 1, 2026

(alphaS)-4-Bromo-alpha-methylbenzenemethanamine → HCID 67997823, compound

https://huagongshe.com/reaction/1426002

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(alphaS)-4-Bromo-alpha-methylbenzenemethanamineHCID 852999—
Reactant1-cyclopropylbut-3-en-2-oneHCID 66652503—
SolventMethanolHCID 887—
ProductHCID 67997823HCID 67997823—

Reaction Conditions

Temperature80 °C

Reaction Steps

(S)-1-(4-Bromophenyl)ethanamine (3.33 g) was added to a solution of 1-cyclopropylbut-3-en-2-one (3.07 g) in methanol (10 mL). The mixture was heated to 80° C. and stirred at this temperature for 10 min. After cooling to room temperature, the mixture was concentrated to give the crude title compound which was used without further purification. Yield: 5.20 g (crude).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08933072B2
Source datasetuspto-grants-2015_01
ORD IDord-d8d93aabaa8f49b4bf5f1b1660e50c36
Source noteuspto-grants-2015_01