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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1426209Generated: October 27, 2026

2-Chloro-5-iodopyridine → 2-tert-Butyl-6-(6-chloro-pyridin-3-ylethynyl)-pyrazolo[1,5-a]pyrimidine

https://huagongshe.com/reaction/1426209

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-iodopyridineHCID 4397176—
Reactant2-tert-Butyl-6-ethynyl-pyrazolo[1,5-a]pyrimidineHCID 58316702—
Product2-tert-Butyl-6-(6-chloro-pyridin-3-ylethynyl)-pyrazolo[1,5-a]pyrimidineHCID 53247328—

Reaction Steps

The title compound, light yellow solid, MS: m/e=311.3 (M+H+), can be prepared in accordance with the general method of example 1 from 2-tert-butyl-6-ethynyl-pyrazolo[1,5-a]pyrimidine (example 21, step 2) and 2-chloro-5-iodopyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08933094B2
Source datasetuspto-grants-2015_01
ORD IDord-9f758becac544722905bbc2d2824b917
Source noteuspto-grants-2015_01