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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1426211Generated: October 27, 2026

3-Bromo-5-chloropyridine → 2-tert-Butyl-6-(5-chloro-pyridin-3-ylethynyl)-pyrazolo[1,5-a]pyrimidine

https://huagongshe.com/reaction/1426211

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-5-chloropyridineHCID 606256—
Reactant2-tert-Butyl-6-ethynyl-pyrazolo[1,5-a]pyrimidineHCID 58316702—
Product2-tert-Butyl-6-(5-chloro-pyridin-3-ylethynyl)-pyrazolo[1,5-a]pyrimidineHCID 53247330—

Reaction Steps

The title compound, light yellow solid, MS: m/e=311.2 (M+H+), can be prepared in accordance with the general method of example 1 from 2-tert-butyl-6-ethynyl-pyrazolo[1,5-a]pyrimidine (example 21, step 2) and 3-bromo-5-chloropyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08933094B2
Source datasetuspto-grants-2015_01
ORD IDord-0a11cc1525174165b8a5a46efe514731
Source noteuspto-grants-2015_01