HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Ethynyl-3-fluorobenzene → 2-tert-Butyl-6-(3-fluoro-phenylethynyl)-[1,2,4]triazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Ethynyl-3-fluorobenzene | HCID 520218 | — |
| Reactant | 6-Bromo-2-tert-butyl-[1,2,4]triazolo[1,5-a]pyrimidine | HCID 58316704 | — |
| Product | 2-tert-Butyl-6-(3-fluoro-phenylethynyl)-[1,2,4]triazolo[1,5-a]pyrimidine | HCID 53247573 | — |
Reaction Steps
The title compound, a light yellow solid, MS: m/e=295.2 (M+H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-tert-butyl-[1,2,4]triazolo[1,5-a]pyrimidine (example 42, step 1) and ethynyl-3-fluorobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08933094B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-ab0ba6b0468149d198d1eb64f7689a18 |
| Source note | uspto-grants-2015_01 |