HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-tert-Butyl-6-trimethylsilanylethynyl-[1,2,4]triazolo[1,5-a]pyrimidine → 2-tert-Butyl-6-(3,4-difluoro-phenylethynyl)-[1,2,4]triazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-tert-Butyl-6-trimethylsilanylethynyl-[1,2,4]triazolo[1,5-a]pyrimidine | HCID 58316698 | — |
| Reactant | 3,4-Difluoro-4-iodobenzene | HCID 67238942 | — |
| Product | 2-tert-Butyl-6-(3,4-difluoro-phenylethynyl)-[1,2,4]triazolo[1,5-a]pyrimidine | HCID 53247574 | — |
Reaction Steps
The title compound, a light yellow solid, MS: m/e=313.1 (M+H+), can be prepared in accordance with the general method of example 43, step 2 from 2-tert-butyl-6-trimethylsilanylethynyl-[1,2,4]triazolo[1,5-a]pyrimidine (example 43, step 1) and 3,4-difluoro-4-iodobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08933094B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-94f1369afed14acfa57912876410bda2 |
| Source note | uspto-grants-2015_01 |