HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67395969, compound → HCID 67396275, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67395969 | HCID 67395969 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67396275 | HCID 67396275 | 99% |
Reaction Steps
To a solution of benzyl 3-{[4-{[(tert-butoxycarbonyl)(methyl)amino]methyl}-3-fluoro-2-(2-fluoropyridin-3-yl)-1H-pyrrol-1-yl]sulfonyl}benzoate (1.03 g) in ethanol (5 mL) was added 10% palladium carbon (50% containing water, 200 mg), and the mixture was stirred for 1 hr under a hydrogen atmosphere. The reaction mixture was filtrated, and concentrated under reduced pressure to give the title compound as a colorless solid (yield 866 mg, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08933105B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-892ec4f4e8ee4318b87ac95b79268e6f |
| Source note | uspto-grants-2015_01 |