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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1426717Generated: November 3, 2026

HCID 67395969, compound → HCID 67396275, compound

https://huagongshe.com/reaction/1426717

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67395969HCID 67395969—
CatalystHCID 178418390HCID 178418390—
SolventEthanolHCID 702—
ProductHCID 67396275HCID 6739627599%

Reaction Steps

To a solution of benzyl 3-{[4-{[(tert-butoxycarbonyl)(methyl)amino]methyl}-3-fluoro-2-(2-fluoropyridin-3-yl)-1H-pyrrol-1-yl]sulfonyl}benzoate (1.03 g) in ethanol (5 mL) was added 10% palladium carbon (50% containing water, 200 mg), and the mixture was stirred for 1 hr under a hydrogen atmosphere. The reaction mixture was filtrated, and concentrated under reduced pressure to give the title compound as a colorless solid (yield 866 mg, 99%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08933105B2
Source datasetuspto-grants-2015_01
ORD IDord-892ec4f4e8ee4318b87ac95b79268e6f
Source noteuspto-grants-2015_01