Ethanol → 1-Boc-4-(hydroxymethyl)-4-methylpiperidine

HRID 142693Notes

Reaction equation

HRID 142693 reaction equation
[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[CH3:1][C:2]1([C:15](=[O:16])[O:17][CH2:18][CH3:19])[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1.[CH3:25][CH2:26][OH:27].[OH2:28]>>[CH3:1][C:2]1([CH2:15][OH:16])[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 702EthanolHCID 962WaterHCID 8028TetrahydrofuranHCID 162182761-tert-Butyl 4-ethyl 4-methylpiperidine-1,4-dicarboxylate

Product 1

HCID 232828431-Boc-4-(hydroxymethyl)-4-methylpiperidine

Sources & evidence

ORD record
ord-5692e33745834948a09bdef4f2b0c2ed
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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