Toluene → HCID 69082691, compound

HRID 1427180Notes

Reaction equation

HRID 1427180 reaction equation
[CH2:1]([OH:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[C:14]1([CH3:20])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.CC1C=C2C([S:26][C:27]3[CH:28]=[CH:29][CH:30]=[C:31]([C:37](Cl)=[O:38])[C:32]=3[C:33]2=[O:36])=CC=1>O>[CH3:20][C:14]1[CH:19]=[C:18]2[C:17]([S:26][C:27]3[CH:28]=[CH:29][CH:30]=[C:31]([C:37]([O:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])=[O:38])[C:32]=3[C:33]2=[O:36])=[CH:16][CH:15]=1

Participants

5

Reactant 3

HCID 1140TolueneHCID 81931-DodecanolHCID 86695882HCID 86695882, compound

Product 1

HCID 69082691HCID 69082691, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.43 g (2.31 mmoles) of 1-dodecyl alcohol are added to a toluene solution containing 0.22 g (0.76 mmoles) of 7-methyl-9-oxo-9H-thioxanthene-1-carbonyl chloride. After stirring 1 hour at room temperature, the mixture is poured in water, the organic phase is separated and washed with water. After evaporation of the solvent the oil is purified by flash chromatography (SiO2—eluent: Petroleum Ether:AcOEt 8:2) obtaining 50 mg of a yellow solid.

Workup

  1. customthe organic phase is separated
  2. washwashed with water
  3. customAfter evaporation of the solvent the oil
  4. customis purified by flash chromatography (SiO2—eluent: Petroleum Ether:AcOEt 8:2)

Sources & evidence

ORD record
ord-6d4ed3a836bc4db58029ace03cf7b1fa
Source dataset
uspto-grants-2015_01
Patent number
US08933142B2

Reaction notes

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