Methylamine → HCID 22335301, compound

HRID 1427375Notes

Reaction equation

HRID 1427375 reaction equation
C([N:8]1[CH2:17][CH2:16][C:15]2[N:14]=[C:13](Cl)[CH:12]=[CH:11][C:10]=2[CH2:9]1)C1C=CC=CC=1.[CH3:19][NH2:20]>>[CH3:19][NH:20][C:13]1[CH:12]=[CH:11][C:10]2[CH2:9][NH:8][CH2:17][CH2:16][C:15]=2[N:14]=1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 162287476-Benzyl-2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine

Product 1

HCID 22335301HCID 22335301, compound

Procedure

6-Benzyl-2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine was reacted with methylamine; deprotection afforded N-methyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-amine.

Sources & evidence

ORD record
ord-e93462630a5747b6a121fb238b5e83a2
Source dataset
uspto-grants-2015_01
Patent number
US08933224B2

Reaction notes

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