Nitromethane → HCID 72709579, compound

HRID 1427679Notes

Reaction equation

HRID 1427679 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2=[O:12].[N+:13]([CH3:16])([O-:15])=[O:14]>O>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2([OH:12])[CH2:16][N+:13]([O-:15])=[O:14]

Participants

4

Reactant 2

HCID 6375NitromethaneHCID 68895-Bromoisatin

Product 1

HCID 72709579HCID 72709579, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
30 °C

Procedure

5-bromoisatin (0.113 g) and nitromethane (0.15 ml) were added to water and the reaction mixture was vigorously stirred at a temperature of 30° C. for 11 hours. The obtained product was extracted with ethyl acetate and the solvent was removed to give pure product.

Workup

  1. extractionThe obtained product was extracted with ethyl acetate
  2. customthe solvent was removed
  3. customto give pure product

Sources & evidence

ORD record
ord-2d066b1687dc43beaf780117aa08c642
Source dataset
uspto-grants-2015_01
Patent number
US08933248B2

Reaction notes

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