Nitromethane → HCID 72709666, compound

HRID 1427692Notes

Reaction equation

HRID 1427692 reaction equation
[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[O:13])[C:5]1=[O:14])[CH:2]=[CH2:3].[N+:15]([CH3:18])([O-:17])=[O:16]>O>[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6]([OH:13])([CH2:18][N+:15]([O-:17])=[O:16])[C:5]1=[O:14])[CH:2]=[CH2:3]

Participants

4

Reactant 2

HCID 6375NitromethaneHCID 17135631-Allylisatin

Product 1

HCID 72709666HCID 72709666, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
40 °C

Procedure

1-allylindoline-2,3-dione (0.093 g) and nitromethane (0.15 ml) were added to water and the reaction mixture was vigorously stirred at a temperature of 40° C. for 24 hours. The obtained product was extracted with ethyl acetate and purified by silica gel column chromatography using ethyl acetate/hexane as eluents to afford pure product.

Workup

  1. extractionThe obtained product was extracted with ethyl acetate
  2. custompurified by silica gel column chromatography
  3. customto afford pure product

Sources & evidence

ORD record
ord-5d903d529e8949ee9ddc4e5c5e7c6ab6
Source dataset
uspto-grants-2015_01
Patent number
US08933248B2

Reaction notes

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