Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nitromethane | HCID 6375 | — |
| Reactant | HCID 2232991 | HCID 2232991 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 72709667 | HCID 72709667 | — |
Reaction Steps
1-(2-bromobenzyl)indoline-2,3-dione (0.158 g) and nitromethane (0.15 ml) were added to water and the reaction mixture was vigorously stirred at a temperature of 30° C. for 30 hours. The obtained product was extracted with ethyl acetate and purified by silica gel column chromatography using ethyl acetate/hexane as eluents to afford pure product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08933248B2 |
|---|
| Source dataset | uspto-grants-2015_01 |
|---|
| ORD ID | ord-761473286cc749dba5342d8577259aff |
|---|
| Source note | uspto-grants-2015_01 |
|---|
