(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → Sweetrex

HRID 1428161Notes

Reaction equation

HRID 1428161 reaction equation
[O:1]=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4]>O>[O:1]=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[OH:1][CH2:2][C:3]([C@H:5]([C@@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])=[O:4]

Participants

3

Reactant 1

HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

Product 1

HCID 3082460Sweetrex

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

In a double-blind, randomised, cross-over design, 34 endurance trained male and 14 female runners and triathletes (35±10 yrs; 70±9 kg; 1.75±0.09 m) completed two 16 km field based runs as fast as possible on two occasions. They received either a glucose gel (GLU) or a glucose+fructose gel (GLU/FRC) to provide CHO at a rate of 1.4 g/min with ad libitum water intake every 3.2 km. Each runner completed a post-exercise questionnaire including 17 questions to assess GI tolerance on a scale from 1 to 10 (from “no problem at all” to “the worst it has ever been”).

Workup

  1. custommale and 14 female runners and triathletes (35±10 yrs; 70±9 kg; 1.75±0.09 m)

Sources & evidence

ORD record
ord-5b41a0ffc48d48d6a5fe1f274c4ca565
Source dataset
uspto-grants-2015_01
Patent number
US08937049B2

Reaction notes

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