Hydrochloric Acid → HCID 117652382, compound

Participants

Reaction Steps

To a mixture of ethyl (7-chloro-2-oxoquinoxalin-1(2H)-yl)acetate (2.21 g) and THF (25 mL) was added a 1 M aqueous NaOH solution (9.0 mL) at room temperature, followed by stirring at the same temperature for 4 hours. The reaction mixture was acidified by the addition of 1 M hydrochloric acid solution and then concentrated under reduced pressure. To the residue was added water, followed by stirring and collecting by filtration. The obtained solid was washed with water to obtain (7-chloro-2-oxoquinoxalin-1(2H)-yl)acetic acid (1.83 g).

Provenance & Evidence