Naphthalene → HCID 14606584, compound

HRID 1428445Notes

Reaction equation

HRID 1428445 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[C:11](Cl)(=[O:15])/[CH:12]=[CH:13]/[CH3:14].[Cl-].[Al+3].[Cl-].[Cl-]>ClCCl>[C:11]([C:9]1[C:10]2[C:5](=[CH:4][CH:3]=[CH:2][CH:1]=2)[CH:6]=[CH:7][CH:8]=1)(=[O:15])/[CH:12]=[CH:13]/[CH3:14]

Participants

5

Reactant 3

HCID 931NaphthaleneHCID 643131trans-Crotonyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 14606584HCID 14606584, compoundYield 64.3%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Naphthalene (128 mg), crotonoyl chloride (124 mg), and aluminium chloride (180 mg) were reacted in dichloromethane (1.5 mL) at from −20° C. to room temperature for 4 hours. The resultant was treated in the same manner as described in Example 1 to obtain the title compound (126 mg).

Workup

  1. additionThe resultant was treated in the same manner

Sources & evidence

ORD record
ord-54a14fdd55934931b8db93cf312e7f57
Source dataset
uspto-grants-2015_01
Patent number
US08937091B2

Reaction notes

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