Anisole → HCID 10899195, compound

HRID 1428447Notes

Reaction equation

HRID 1428447 reaction equation
[C:1]1([O:7][CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:9](Cl)(=[O:13])/[CH:10]=[CH:11]/[CH3:12].[Cl-].[Al+3].[Cl-].[Cl-]>ClCCl>[CH3:8][O:7][C:1]1[CH:6]=[CH:5][C:4]([C:9](=[O:13])/[CH:10]=[CH:11]/[CH3:12])=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 7519AnisoleHCID 643131trans-Crotonyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 10899195HCID 10899195, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Anisole (0.3 mL), crotonoyl chloride (24 mg), and aluminium chloride (160 mg) were reacted in dichloromethane (1.5 mL) at from −50° C. to room temperature for 4 hours. The resultant was treated in the same manner as described in Example 1 to obtain the title compound (75 mg).

Workup

  1. additionThe resultant was treated in the same manner

Sources & evidence

ORD record
ord-8891c423b5224410bf34641fc15d8827
Source dataset
uspto-grants-2015_01
Patent number
US08937091B2

Reaction notes

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