HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → 4-Chlorobutyrophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | 4-Chlorobutyryl chloride | HCID 78370 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Chlorobutyrophenone | HCID 253533 | 881% |
Reaction Steps
Benzene (0.5 mg), 4-chlorobutyryl chloride (141 mg), and aluminium chloride (170 mg) were reacted in dichloromethane (1.5 mL) at from 0° C. to room temperature for 4 hours. The resultant was treated in the same manner as described in Example 1 to obtain the title compound (10.3 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08937091B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-e5551fd393ac428cb99cb8742d23c706 |
| Source note | uspto-grants-2015_01 |