反应详情

A solution of D7 (0.05 g, 0.17 mmol) and triethylorthopropionate (0.462 ml, 2.556 mmol) in xylene (1 ml) was heated in a sealed tube at 180° C. for 2 h. After cooling, the resulting mixture was concentrated in vacuo. The residue thus obtained was triturated with Et2O to yield final compound E10 (0.042 g, 74%).

1. temperatureAfter cooling
2. concentrationthe resulting mixture was concentrated in vacuo
3. customThe residue thus obtained
4. customwas triturated with Et2O