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HRID1429

反应详情

EQUATION

反应方程式

HRID 1429 的结构方程式

REACTANTS

反应物

3
结构：N[C@@H](CS)C(=O)O
HCID5862

L-Cysteine

C3H7NO2S

结构：CC(C)[C@H](N)C(=O)O
HCID6287

L-Valine

C5H11NO2

结构：CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(=O)[O-].[K+]
HCID23664709

Penicillin G potassium

C16H17KN2O4S

PRODUCTS

生成物

1
结构：CC1(C)S[C@@H]2[C@H](NC(=O)CCC[C@H](N)C(=O)O)C(=O)N2[C@H]1C(=O)O
HCID440723

Isopenicillin N

C14H21N3O6S

PROCEDURE

实验过程

The first two steps in the biosynthesis of penicillin in P. chrysogenum are the condensation of the three amino acids L-5-amino-5-carboxypentanoic acid (L-α-aminoadipic acid) (A), L-cysteine (C) and L-valine (V) into the tripeptide LLD-ACV, followed by cyclization of this tripeptide to form isopenicillin N. This compound contains the typical β-lactam structure.