HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67382367, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 67417383 | HCID 67417383 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 67382367 | HCID 67382367 | 98% |
Reaction Steps
Compound 1b (34.7 g, 90 mmol) was treated with HCl (g) in dioxane (700 mL) at rt overnight. Concentrated in vacuo gave the hydrochloride salt of compound 1c which was used for next step without any further purification (28.3 g, 98% yield). MS (ESI+): 286 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940722B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-c5ab2bb812d24357a417df158ddf4a36 |
| Source note | uspto-grants-2015_01 |