HRID1429528

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID182236

1-Propanesulfonyl chloride, 2-methyl-

C4H9ClO2S

结构：CCCc1cnc(N2CCC(Oc3nc4ccc(C5=CCNCC5)cc4s3)CC2)nc1

HCID67462795

未命名化合物

PRODUCTS

生成物

结构：CCCc1cnc(N2CCC(Oc3nc4ccc(C5=CCN(S(=O)(=O)CC(C)C)CC5)cc4s3)CC2)nc1

HCID54596401

未命名化合物

PROCEDURE

实验过程

Example 11 was prepared from Compound 1E and 2-methylpropane-1-sulfonyl chloride in a similar manner to the procedure described in Example 1. LCMS (M+H)+=556.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ffdaff941f724ac9a408b86b5aa8b507
来源数据集: uspto-grants-2015_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08940716B2
来源说明: uspto-grants-2015_01

反应 SMILES

[CH2:1]([C:4]1[CH:5]=[N:6][C:7]([N:10]2[CH2:15][CH2:14][CH:13]([O:16][C:17]3[S:18][C:19]4[CH:25]=[C:24]([C:26]5[CH2:27][CH2:28][NH:29][CH2:30][CH:31]=5)[CH:23]=[CH:22][C:20]=4[N:21]=3)[CH2:12][CH2:11]2)=[N:8][CH:9]=1)[CH2:2][CH3:3].[CH3:32][CH:33]([CH3:39])[CH2:34][S:35](Cl)(=[O:37])=[O:36]>>[CH2:34]([S:35]([N:29]1[CH2:28][CH:27]=[C:26]([C:24]2[CH:23]=[CH:22][C:20]3[N:21]=[C:17]([O:16][CH:13]4[CH2:14][CH2:15][N:10]([C:7]5[N:8]=[CH:9][C:4]([CH2:1][CH2:2][CH3:3])=[CH:5][N:6]=5)[CH2:11][CH2:12]4)[S:18][C:19]=3[CH:25]=2)[CH2:31][CH2:30]1)(=[O:37])=[O:36])[CH:33]([CH3:39])[CH3:32]