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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1429528Generated: November 1, 2026

1-Propanesulfonyl chloride, 2-methyl- → 6-(1-(Isobutylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl)-2-(1-(5-propylpyrimidin-2-yl)piperidin-4-yloxy)benzo[d]thiazole

https://huagongshe.com/reaction/1429528

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Propanesulfonyl chloride, 2-methyl-HCID 182236—
Reactant2-(1-(5-Propylpyrimidin-2-yl)piperidin-4-yloxy)-6-(1,2,3,6-tetrahydropyridin-4-yl)benzo[d]thiazoleHCID 67462795—
Product6-(1-(Isobutylsulfonyl)-1,2,3,6-tetrahydropyridin-4-yl)-2-(1-(5-propylpyrimidin-2-yl)piperidin-4-yloxy)benzo[d]thiazoleHCID 54596401—

Reaction Steps

Example 11 was prepared from Compound 1E and 2-methylpropane-1-sulfonyl chloride in a similar manner to the procedure described in Example 1. LCMS (M+H)+=556.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08940716B2
Source datasetuspto-grants-2015_01
ORD IDord-ffdaff941f724ac9a408b86b5aa8b507
Source noteuspto-grants-2015_01