HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 6-Bromo-2-(piperidin-4-yloxy)thiazolo[4,5-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 6-Bromo-2-(piperidin-4-yloxy)-benzothiazole | HCID 67466824 | — |
| Reactant | tert-Butyl 4-(6-bromothiazolo[4,5-b]pyridin-2-yloxy)piperidine-1-carboxylate | HCID 68208481 | — |
| Product | 6-Bromo-2-(piperidin-4-yloxy)thiazolo[4,5-b]pyridine | HCID 67462789 | — |
Reaction Steps
Compound 21C was prepared from Compound 21B and TFA in a similar manner to the procedure described for Compound 1B in Example 1. LC/MS (m/z)=314 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940716B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-f0817a01803f4defba993a9b685c8547 |
| Source note | uspto-grants-2015_01 |