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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1429589Generated: November 3, 2026

Methyl 3-(chlorosulfonyl)propanoate → Methyl 3-(4-(2-(1-(5-methylpyrazin-2-yl)piperidin-4-yloxy)benzo[d]thiazol-6-yl)-5,6-dihydropyridin-1(2H)-ylsulfonyl)propanoate

https://huagongshe.com/reaction/1429589

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-(chlorosulfonyl)propanoateHCID 4962888—
Reactant2-(1-(5-Methylpyrazin-2-yl)piperidin-4-yloxy)-6-(1,2,3,6-tetrahydropyridin-4-yl)benzo[d]thiazoleHCID 71269938—
ProductMethyl 3-(4-(2-(1-(5-methylpyrazin-2-yl)piperidin-4-yloxy)benzo[d]thiazol-6-yl)-5,6-dihydropyridin-1(2H)-ylsulfonyl)propanoateHCID 71269985—

Reaction Steps

Compound 50D was prepared from Compound 50C and methyl 3-(chlorosulfonyl)propanoate in a similar manner to the procedure described for Compound Example 16.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08940716B2
Source datasetuspto-grants-2015_01
ORD IDord-246d2f8246b84a08a0a8a3b0b82aef12
Source noteuspto-grants-2015_01