Isopropanol hydrochloride → HCID 59805851, compound

Participants

Reaction Steps

A solution of D1 (7.06 g, 20.4 mmol) and hydrochloric acid/isopropanol (6N, 100 ml) in methanol (100 ml) was stirred at room temperature for 2 h. After this period, solvents were evaporated in vacuo and the residue triturated with acetonitrile. The solid product was filtered off and dried to give D2 as the di-hydrochloride salt (6.05 g, 95%). C10H13F3N4 requires 246; Found 247 (MH+)

Provenance & Evidence