N-[5-(2-tert-butyl-pyridin-4-yl)-4-methyl-thiazol-2-yl]acetamide → 5-(2-Tert-butylpyridin-4-yl)-4-methylthiazol-2-amine

Participants

Reaction Steps

N-[4-methyl-5-(2-tert-butyl-4-pyridyl)-1,3-thiazol-2-yl]acetamide (90 mg) in ethanol (4.5 ml) and 6N hydrochloric acid (0.5 ml) is heated in a Emrys Optimiser personal chemistry microwave at 100° C. for 90 minutes. Cooling of the reaction mixture and filtration gives the title compound.

Provenance & Evidence