反应详情

温度

100 °C

A mixture of 5-acetyl-2-amino-4-methylthiazole (12.5 g) and N,N-dimethylformamide-dimethylacetal (35.4 ml) is heated for 15 hours at 100° C. After cooling to room temperature the reaction mixture is evaporated, triturated with ethyl acetate, and filtered to give the title compound as an orange solid. MS (Method D) M+H 267.

1. temperatureAfter cooling to room temperature the reaction mixture
2. customis evaporated
3. customtriturated with ethyl acetate
4. filtrationfiltered