HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Iodosuccinimide → N-(5-Iodo-4-methyl-2-thiazolyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Reactant | 2-Acetamido-4-methylthiazole | HCID 280907 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N-(5-Iodo-4-methyl-2-thiazolyl)acetamide | HCID 57417074 | — |
Reaction Steps
N-Iodosuccinimide (4.75 g) is added portion wise to a solution of N-(4-methyl-thiazol-2-yl)-acetamide (3 g) in acetonitrile (60 ml) at room temperature. After 5 minutes a precipitate forms which is collected by filtration and washed with cold acetonitrile to give the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940771B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-741d3a2ff74a4adaac463dc967dae66d |
| Source note | uspto-grants-2015_01 |