反应详情

A mixture of (S)-azetidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester (2.5 g) and 7M ammonia in methanol (10 ml) is stood at room temperature for 18 hours in a sealed vessel. The reaction mixture is then evaporated to give the title compound as a white solid which is used without further purification. MS M+H 235.1 and M−H 233.1.

1. customThe reaction mixture is then evaporated