Ammonia → HCID 57420322, compound

Participants

Reaction Steps

A mixture of (3R,7aS)-7a-difluoromethyl-3-trichloromethyl-tetrahydro-pyrrolo[1,2-c]oxazol-1-one (0.19 g) and 7M ammonia in methanol (4 ml) is stood at room temperature for 3 days in a sealed vessel. The reaction mixture is then filtered and evaporated to give the title compound as a pale brown oil which is used without further purification. MS (Method D) M+H 165.

Provenance & Evidence