Pyrazole → HCID 86681296, compound

HRID 1430227Notes

Reaction equation

HRID 1430227 reaction equation
CN(C)C1[CH:4]=[C:5]([CH2:9][OH:10])[CH:6]=[CH:7][CH:8]=1.[NH:12]1[CH:16]=[CH:15][CH:14]=[N:13]1.CC1(C)C(C)(C)OB(C2C=NNC=2)O1>>[O:10]1[CH2:8][CH2:7][CH2:6][CH:5]([CH2:4][N:12]2[CH:16]=[CH:15][CH:14]=[N:13]2)[CH2:9]1

Participants

4

Reactant 3

HCID 1048PyrazoleHCID 90133m-(Dimethylamino)benzyl alcoholHCID 27740104-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Product 1

HCID 86681296HCID 86681296, compound

Procedure

The title compound was prepared by substituting (tetrahydro-2H-pyran-3-yl)methanol for (3-(dimethylamino)phenyl)methanol and 1H-pyrazole for 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole in EXAMPLE 34A.

Sources & evidence

ORD record
ord-b346bdf5b6ad4e65b9bc6d15b3c9aa2b
Source dataset
uspto-grants-2015_01
Patent number
US08940737B2

Reaction notes

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