Pyrazole → HCID 86681302, compound

HRID 1430239Notes

Reaction equation

HRID 1430239 reaction equation
CN(C)[C:3]1[CH:4]=[C:5]([CH2:9]O)[CH:6]=[CH:7][CH:8]=1.[NH:12]1[CH:16]=[CH:15][CH:14]=[N:13]1.[CH3:17][C:18]1(C)[C:22](C)(C)OB(C2C=NNC=2)O1>>[CH3:17][C:18]1([CH3:22])[C@H:4]2[CH2:3][C@@H:8]1[CH2:7][CH2:6][C@H:5]2[CH2:9][N:12]1[CH:16]=[CH:15][CH:14]=[N:13]1

Participants

4

Reactant 3

HCID 1048PyrazoleHCID 90133m-(Dimethylamino)benzyl alcoholHCID 27740104-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Product 1

HCID 86681302HCID 86681302, compound

Procedure

The title compound was prepared by substituting ((1S,2R,5S)-6,6-dimethylbicyclo[3.1.1]heptan-2-yl)methanol for (3-(dimethylamino)phenyl)methanol and pyrazole for 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole in EXAMPLE 34A.

Sources & evidence

ORD record
ord-6866c52067f348b3b14752be6fed99df
Source dataset
uspto-grants-2015_01
Patent number
US08940737B2

Reaction notes

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