Sodium Hydroxide → HCID 66024353, compound

Participants

Reaction Conditions

Reaction Steps

A solution of EXAMPLE 97A (2.14 g) in diethyl ether (10 mL) was added dropwise to a suspension of LiAlH4 (0.380 g) in diethyl ether (20 mL). Once the addition was finished, the mixture was refluxed for 90 minutes, and then cooled to 0° C. NaOH (2N, aqueous, 50 mL) was then added slowly. The mixture was extracted with ethyl acetate (300 mL) and washed with brine and dried over Na2SO4. Filtration and evaporation of the solvent gave the title compound.

Provenance & Evidence