HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylaniline → HCID 86681316, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylaniline | HCID 7515 | — |
| Reactant | 2-Fluoro-4-iodo-3-methylpyridine | HCID 11776298 | — |
| Product | HCID 86681316 | HCID 86681316 | — |
Reaction Steps
2-Fluoro-4-iodo-3-methylpyridine (700 mg) in N-methylaniline (2.5 mL) was heated at 180° C. in a Biotage Initiator microwave reactor for 18 hours. The reaction mixture was loaded onto a silica gel cartridge, and was eluted with 0-100% dichloromethane in hexanes to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940737B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-0dec06cb6a6942d38abf099f40044ff5 |
| Source note | uspto-grants-2015_01 |