反应详情

To a mixture of 3,4-dibromo-5-hydroxyfuran-2(5H)-one (0.5 g, 1.939 mmol) in toluene (5 mL, 1.939 mmol) was added AlCl3 (0.310 g, 2.327 mmol) at room temperature. The mixture was stirred at room temperature overnight. The reaction was quenched with water, extracted with EtOAc (3×20 mL), dried over anhydrous MgSO4, and filtered. The filtrate was concentrated under reduced pressure to give the title compound without further purification. LCMS m/z=332.8 [M+H]+.

1. customThe reaction was quenched with water
2. extractionextracted with EtOAc (3×20 mL)
3. dry with materialdried over anhydrous MgSO4
4. filtrationfiltered
5. concentrationThe filtrate was concentrated under reduced pressure