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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 143084Generated: October 30, 2026

Ethyl 4-chloro-6-methyl-2-(methylsulfanyl)pyrimidine-5-carboxylate → ethyl 4-({3-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]phenyl}amino)-6-methyl-2-(methylthio)-5-pyrimidinecarboxylate

https://huagongshe.com/reaction/143084

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-chloro-6-methyl-2-(methylsulfanyl)pyrimidine-5-carboxylateHCID 22225416—
Reactant2-[2-(3-aminophenyl)ethyl]-1H-isoindole-1,3(2H)-dioneHCID 67219583—
Productethyl 4-({3-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]phenyl}amino)-6-methyl-2-(methylthio)-5-pyrimidinecarboxylateHCID 58296311—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-cdd43662a56446698881302907f81fc8
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)