Isopropanol → propan-2-yl 4-[[3,5-bis(trifluoromethyl)phenyl]methyl-methoxycarbonylamino]-8-bromo-2-cyclopropyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinoline-1-carboxylate
Reaction equation
[CH:42]([CH3:43])([CH3:44])[OH:45].[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]([CH:8]2[CH2:9][CH:10]([CH:26]3[CH2:27][CH2:28]3)[N:11]([C:23](=[O:24])[Cl:25])[c:12]3[c:13]([Br:22])[cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][c:17]32)[C:29](=[O:30])[O:31][CH3:32])[cH:33][c:34]([C:36]([F:37])([F:38])[F:39])[cH:35]1)([F:40])[F:41]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH2:6][N:7]([CH:8]2[CH2:9][CH:10]([CH:26]3[CH2:27][CH2:28]3)[N:11]([C:23](=[O:24])[O:45][CH:42]([CH3:43])[CH3:44])[c:12]3[c:13]([Br:22])[cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][c:17]32)[C:29](=[O:30])[O:31][CH3:32])[cH:33][c:34]([C:36]([F:37])([F:38])[F:39])[cH:35]1)([F:40])[F:41]Participants
3
Sources & evidence
- ORD record
- ord-a615cf7718494cc8ac9c4ea026823368
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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