HCID 67284525, compound → HCID 67285313, compound

HRID 1431227Notes

Reaction equation

HRID 1431227 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([NH:8][C:9](=[O:17])[CH:10]([CH3:16])[C:11]([O:13]CC)=[O:12])[CH:5]=[CH:6][CH:7]=1>C1COCC1>[F:1][C:2]1[CH:3]=[C:4]([NH:8][C:9](=[O:17])[CH:10]([CH3:16])[C:11]([OH:13])=[O:12])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 67284525HCID 67284525, compound

Product 1

HCID 67285313HCID 67285313, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Prepared according to Procedure B using ethyl 3-(3-fluorophenylamino)-2-methyl-3-oxopropanoate (21.0 g, 87.8 mmol) in THF (80 mL) to give 3-(3-fluorophenylamino)-2-methyl-3-oxopropanoic acid as a white solid. Mass Spectrum (ESI) m/e=212.1 (M+1).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-952974dfc2a94ad5a9e49063a0621e6a
Source dataset
uspto-grants-2015_01
Patent number
US08940724B2

Reaction notes

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