HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 4-Chloro-5,7-difluoro-3-methyl-2-(piperidin-1-yl)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 2,4-Dichloro-5,7-difluoro-3-methylquinoline | HCID 59631040 | — |
| Product | 4-Chloro-5,7-difluoro-3-methyl-2-(piperidin-1-yl)quinoline | HCID 59631153 | — |
Reaction Steps
Prepared according to Procedure G using 2,4-dichloro-5,7-difluoro-3-methylquinoline (300 mg, 1.21 mmol) and piperidine in to give 4-chloro-5,7-difluoro-3-methyl-2-(piperidin-1-yl)quinoline. Mass Spectrum (ESI) m/e=297.1 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940724B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-154a19155c204e10b32e6597e5c20903 |
| Source note | uspto-grants-2015_01 |