HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-6-(tributylstannyl)pyridine → 4-Chloro-5,7-difluoro-2-(6-methoxypyridin-2-yl)-3-methylquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-6-(tributylstannyl)pyridine | HCID 10524891 | — |
| Reactant | 2,4-Dichloro-5,7-difluoro-3-methylquinoline | HCID 59631040 | — |
| Product | 4-Chloro-5,7-difluoro-2-(6-methoxypyridin-2-yl)-3-methylquinoline | HCID 59631482 | — |
Reaction Steps
Prepared according to Procedure E using 2,4-dichloro-5,7-difluoro-3-methylquinoline (250 mg, 1.01 mmol) and 2-methoxy-6-(tributylstannyl)pyridine to give 4-chloro-5,7-difluoro-2-(6-methoxypyridin-2-yl)-3-methylquinoline. Mass Spectrum (ESI) m/e=321.1 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940724B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-17e63e8644c34e3da21a7f56d3688195 |
| Source note | uspto-grants-2015_01 |