HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Piperidone → 1-(4-Chloro-5,7-difluoro-3-methylquinolin-2-yl)piperidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Piperidone | HCID 12665 | — |
| Reactant | 2,4-Dichloro-5,7-difluoro-3-methylquinoline | HCID 59631040 | — |
| Product | 1-(4-Chloro-5,7-difluoro-3-methylquinolin-2-yl)piperidin-2-one | HCID 59631552 | — |
Reaction Steps
Prepared according to Procedure I using 2,4-dichloro-5,7-difluoro-3-methylquinoline (250 mg, 1.01 mmol) and piperidin-2-one to give 1-(4-chloro-5,7-difluoro-3-methylquinolin-2-yl)piperidin-2-one. Mass Spectrum (ESI) m/e=311.0 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08940724B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-a3fdce276f8542a19885881444239e6c |
| Source note | uspto-grants-2015_01 |