HCID 59631204, compound → HCID 59631427, compound

HRID 1431353Notes

Reaction equation

HRID 1431353 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9](=[O:17])[CH:10]([CH3:16])[C:11]([O:13]CC)=[O:12])=[CH:4][C:3]=1[O:18][CH3:19]>C1COCC1>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9](=[O:17])[CH:10]([CH3:16])[C:11]([OH:13])=[O:12])=[CH:4][C:3]=1[O:18][CH3:19]

Participants

3

Reactant 1

HCID 59631204HCID 59631204, compound

Product 1

HCID 59631427HCID 59631427, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Prepared according to Procedure B using ethyl 3-(4-chloro-3-methoxyphenylamino)-2-methyl-3-oxopropanoate (3.7 g, 12.95 mmol) in THF (13.0 mL) to give 3-(4-chloro-3-methoxyphenylamino)-2-methyl-3-oxopropanoic acid. Mass Spectrum (ESI) m/e=258.1 (M+1).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-9cc882d7ebe14ac383158cfc464c134e
Source dataset
uspto-grants-2015_01
Patent number
US08940724B2

Reaction notes

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