Lithium ion → 2,6-Di-tert-butyl-4-[1-(4-hydroxymethyl-thiazole-2-sulfonyl)-piperidin-4-ylsulfanyl]-phenol

HRID 143145Notes

Reaction equation

HRID 143145 reaction equation
[Al+3:37].[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([S:16][CH:17]2[CH2:18][CH2:19][N:20]([S:23](=[O:24])(=[O:25])[c:26]3[s:27][cH:28][c:29]([C:31](=[O:32])[O:33][CH2:34][CH3:35])[n:30]3)[CH2:21][CH2:22]2)[cH:8][c:9]([C:12]([CH3:13])([CH3:14])[CH3:15])[c:10]1[OH:11].[H-:36].[H-:39].[H-:40].[H-:41].[Li+:38]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([S:16][CH:17]2[CH2:18][CH2:19][N:20]([S:23](=[O:24])(=[O:25])[c:26]3[s:27][cH:28][c:29]([CH2:31][OH:32])[n:30]3)[CH2:21][CH2:22]2)[cH:8][c:9]([C:12]([CH3:13])([CH3:14])[CH3:15])[c:10]1[OH:11]

Participants

5

Reactant 4

HCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 86635437Ethyl 2-[4-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-piperidine-1-sulfonyl]-thiazole-4-carboxylate

Product 1

HCID 251681512,6-Di-tert-butyl-4-[1-(4-hydroxymethyl-thiazole-2-sulfonyl)-piperidin-4-ylsulfanyl]-phenol

Sources & evidence

ORD record
ord-37dfe455773f40649d1471c0de356447
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…